Immunopathologic Studies in Relapsing Polychondritis
نویسندگان
چکیده
منابع مشابه
Immunopathologic studies in relapsing polychondritis.
Serial studies have been performed on three patients with relapsing polychondritis in an attempt to define a potential immunopathologic role for degradation constituents of cartilage in the causation and/or perpetuation of the inflammation observed. Crude proteoglycan preparations derived by disruptive and differential centrifugation techniques from human costal cartilage, intact chondrocytes g...
متن کاملRELAPSING POLYCHONDRITIS Biologics in Relapsing Polychondritis: A Literature Review
Background: There is no standardized therapeutic protocol for relapsing polychondritis (RP). Emergence of biologics holds much hope in the management of this connective tissue disease. Objectives: To evaluate the efficacy and safety of biologics in patients with active RP. Methods: A systematic review of the literature using PubMed was performed through December 2010. MeSH terms and keywords we...
متن کاملRelapsing polychondritis.
Relapsing polychondritis, an uncommon, chronic, multisystem disorder characterized by recurrent episodes of inflammation of cartilaginous tissues, can be life-threatening, debilitating, and difficult to diagnose. This review is based on the authors' experience with 36 patients with relapsing polychondritis who were followed from 1980 to 1997, 30 patients located elsewhere who completed a detail...
متن کاملRelapsing Polychondritis
Relapsing polychondritis (RP) is a rare systemic disease characterized by recurrent, widespread chondritis of the auricular, nasal, and tracheal cartilages. Additional clinical features include audiovestibular dysfunction, ocular inflammation, vasculitis, myocarditis, and nonerosive arthritis. Although the cause remains unknown, the etiology is suspected to be autoimmune. We describe a case of ...
متن کاملRelapsing polychondritis.
Relapsing polychondritis (RPC) is a unique and rarely observed autoimmune condition regarded as recurrent extensive chondritis of the auricular, nasal, and tracheal cartilages. Moreover, heart, main arteries, skin, and eyes may be involved. Several forms of clinical manifestations may be seen, and the pathogenesis still remains anonymous. A concomitant disease, particularly myelodysplasia or ot...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1973
ISSN: 0021-9738
DOI: 10.1172/jci107215